Analogical reasoning relies on subprocesses of long-term memory and problem-solving. Stress, with its accompanying hormones dehydroepiandrosterone and cortisol, has been shown to impair memo...

Numerous studies have documented the detrimental impact of age-based stereotype threat on older adults' cognitive performance and especially on veridical memory. However, far fewer studies have investigated the impact of ABST on older adults' memory distortion. Here, we review the subset of research examining memory distortion and provide evidence for the role of stereotype threat as a powerful socio-emotional factor that impacts age-related susceptibility to memory distortion. In this review we define memory distortion as errors in memory that are associated (...) with gist-based errors or source misattributions. Whereas, some of the reviewed experiments support the conclusion that ABST should be considered in the context of age-related differences in memory distortion, others reported little or no impact of stereotype threat. These discrepancies suggest that the role of ABST, and socio-emotional processes generally, in age-related changes in memory distortion are less clear. In this review, we argue that ABST does play an important role in age-related changes in memory distortion. We present evidence suggesting that discrepancies in the reviewed literature may be reconciled when evaluated in the context of the leading theories about stereotype threat: the Executive Resource Depletion hypothesis and the Regulatory Focus theory. We also discuss how differences in methodology and participant characteristics can account for a priori contradictory results in the literature. Finally, we propose some recommendations for researchers and practitioners when assessing memory in older adults. (shrink)

Cultural effects can influence the results of causal genetic analyses, such as Mendelian randomisation, but the potential influences of culture on genotype–phenotype associations are not currently well understood. Different genetic variants could be associated with different phenotypes in different populations, or culture could confound or influence the direction of the association between genotypes and phenotypes in different populations.

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

This book's importance is derived from three sources: careful conceptualization of teacher induction from historical, methodological, and international perspectives; systematic reviews of research literature relevant to various aspects of teacher induction including its social, cultural, and political contexts, program components and forms, and the range of its effects; substantial empirical studies on the important issues of teacher induction with different kinds of methodologies that exemplify future directions and approaches to the research in teacher induction.

Preparing the Next Generation of Oral Historians is an invaluable resource to educators seeking to bring history alive for students at all levels. Filled with insightful reflections on teaching oral history, it offers practical suggestions for educators seeking to create curricula, engage students, gather community support, and meet educational standards. By the close of the book, readers will be able to successfully incorporate oral history projects in their own classrooms.

Physicists regularly invoke universal laws, such as those of motion and electromagnetism, to explain events. Biological and medical scientists have no such laws. How then do they acquire a reliable body of knowledge about biological organisms and human disease? One way is by repeatedly returning to, manipulating, observing, interpreting, and reinterpreting certain subjects—such as flies, mice, worms, or microbes—or, as they are known in biology, “model systems.” Across the natural and social sciences, other disciplinary fields have developed canonical examples that (...) have played a role comparable to that of biology’s model systems, serving not only as points of reference and illustrations of general principles or values but also as sites of continued investigation and reinterpretation. The essays in this collection assess the scope and function of model objects in domains as diverse as biology, geology, and history, attending to differences between fields as well as to epistemological commonalities. Contributors examine the role of the fruit fly Drosophila and nematode worms in biology, troops of baboons in primatology, box and digital simulations of the movement of the earth’s crust in geology, and meteorological models in climatology. They analyze the intensive study of the prisoner’s dilemma in game theory, ritual in anthropology, the individual case in psychoanalytic research, and Athenian democracy in political theory. The contributors illuminate the processes through which particular organisms, cases, materials, or narratives become foundational to their fields, and they examine how these foundational exemplars—from the fruit fly to Freud’s Dora—shape the knowledge produced within their disciplines. Contributors Rachel A. Ankeny Angela N. H. Creager Amy Dahan Dalmedico John Forrester Clifford Geertz Carlo Ginzburg E. Jane Albert Hubbard Elizabeth Lunbeck Mary S. Morgan Josiah Ober Naomi Oreskes Susan Sperling Marcel Weber M. Norton Wise. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bataille and Mysticism: A “Dazzling Dissolution”Amy Hollywood (bio)Within Georges Bataille’s texts of the late 1930s and 1940s, in particular those later brought together in the tripartite Atheological Summa, he repeatedly suggests that his primary models for writing and experience are the texts of the Christian and non-Western mystical traditions (often represented, in Bataille, by women’s writings) and those of Friedrich Nietzsche. 1 Inner Experience opens with evocations of Nietzsche, (...) and the final volume of the trilogy, On Nietzsche, is “devoted” to his work. References to mystical writings occur throughout Inner Experience and Guilty, and significant portions of both texts can be read as providing “guides” for inner experience analogous to the “itineraries” of Angela of Foligno (d. 1309) and Teresa of Avila (d. 1582) or as spiritual daybooks like those of Mechthild of Magdeburg (d. ca. 1275). These models are, I think, the key to understanding Bataille’s own writing strategies in the Atheological Summa. 2 Despite their apparent divergence, moreover, Bataille insists that mystical and Nietzschean texts reflect and are constitutive of the same experience and writing practice.Like both Nietzsche and the mystics, Bataille’s “antigeneric” writing mixes genres and styles within and between texts. 3 Throughout the course of his career, experience and writing are in a constant state of movement, flux, or chaos (to echo Bataille’s self-description in On Nietzsche). The Atheological Summa encapsulates within what purport to be three unified books the diversity of genres and styles that run throughout Bataille’s corpus as a whole. They contain ample quotation of Nietzsche’s texts and those of the mystics—undigested hunks and fragments of these allusive writings 4 —together with philosophical reflections, confessional meditations, diary fragments, letters, and, at the end of On Nietzsche, a set of six brief historical and theoretical appendices. Anything broaching traditional textual commentary is reserved for the margins of these nonbooks. Like many mystics, particularly women who were denied access to the traditional genres of sermon, biblical commentary, and philosophical or theological treatise, and like Nietzsche, who eschews and subverts traditional genre distinctions, Bataille comments and critiques through practice rather than exposition. Although Bataille acknowledges the oddity of his coupling the mystics and Nietzsche, he also rigorously defends it, arguing for a mystical and ecstatic experience in Nietzsche’s work. 5 As I hope to show, Bataille’s [End Page 74] experience of the failures of mysticism and of Nietzsche speak to each other and lead to Bataille’s necessary apostasy as his true discipleship.Repetition of the divergences between Bataille and the mystics, first stated by Bataille himself in Inner Experience, has become something of a commonplace, yet his claims have not been sufficiently explored or challenged. So, for example, Alain Arnauld and Giséle Excoffon-Lafarge unproblematically assert that despite all proximities between Bataille’s texts and those of the mystics, they differ in their aims or aimlessness. Michel Surya joins a host of other scholars whose primary concern is to demonstrate (against the insinuations of Sartre, made now almost fifty years ago) that Bataille was not a Christian. Whereas the mystics’ path ends with the divine encounter, Bataille renounces all objects, aims, or end for his quest and his desire. 6 Most importantly, he rejects all idealism and any hope for salvation. Bataille himself insists on his divergence from the Christian mystics in Inner Experience and Guilty. At the same time, his citations and mimings of central texts from the Christian mystical tradition show that what fascinates him within these writings is precisely the moment in which the soul desires “to live without a why,” embracing the suffering of hell—understood as the absence of/from the “object” of desire—as desire. 7 In a move later echoed by Jacques Lacan, Bataille claims that some medieval mystics attained that beyond of which he writes, but without knowing anything about it: “Exuberance is the point where we let go of Christianity. Angela of Foligno attained it and described it, but didn’t know it.” 8Commentators follow Bataille in resisting his identification with the mystics, then, whereas Nietzsche is a less troubling model for Bataille and his readers. In fact, Bataille... (shrink)

Research into human trafficking for sexual exploitation often conceptualizes the experience through the lens of migration and/or sex work. Women’s bodies are often politicized and the corporeal experiences of trafficking are neglected. The gendered stigma attached to women who have been trafficked for sexual exploitation is clearly evident across cultures and requires further analysis as part of wider societal responses to sexual violence. Through the analysis of letters written by women who have been trafficked and sexually exploited from post-Soviet countries (...) to Israel, this article argues that conceptualizing women’s bodies as bounded spaces allows an investigation of the transgression of those boundaries and opens up a thought-provoking framework for theorizing experiences of, and social responses to, sexual violence, stigma and social exclusion. It explores themes of pollution and dirt as ways to communicate social exclusion through references to boundaries crossed and spaces rendered abject. Women’s narratives of trafficking are examined utilizing the theory of abjection, and the embodied effects of sexual violence and body boundary transgression are elucidated. This analysis shows that the women in this study articulate an embodied narrative of trafficking that is experienced in relation to body boundaries and expressed through motifs of dirt, smell, disgust and pollution. (shrink)

The 17th century author François Poulain de la Barre was an important contributor to a pivotal moment in the history of feminist thought. Poulain borrows from many of Descartes’s doctrines, including his dualism, distrust of epistemic authority, accounts of imagination, and passion, and at least some aspects of his doxastic voluntarism; here I examine how he uses a Cartesian notion of prejudice for an anti-essentializing philosophy of women’s education and the formation of the tastes, talents and interests of individuals. ‘Prejudice’ (...) remains Descartes’s notion of an entrenched, yet self-imposed doxastic commitment, but also takes on the sense of social-political group bias, founded on custom, transmitted through education, serving interests, and forming social expectations. Poulain also expands on the Cartesian notion and themes by emphasizing widespread, yet unjustified social opinions in favor of the status quo in both epistemic practices and epistemic authorities, while considering how biased beliefs about sexual difference and gender identity can be internalized even by those who suffer most from them. At the same time, he shows how powerful Cartesian concepts can be for feminist methodology, even though they might also be put to problematic uses (as Malebranche did). (shrink)

This report offers recommendations to physicians who provide information or services through online sites. The recommendations maintain that physicians responsible for health-related information should ensure that it is accurate, timely, reliable, and scientifically sound. Also, advice to online users with whom physicians do not have preexisting relationships or the use of decision-support programs that generate personalized information directly transmitted to users should be consistent with general and specialty-specific standards. In particular, these standards should address truthfulness, protection of privacy, informed consent, (...) and disclosures including limitations inherent in the technology. Finally, physicians who establish or are involved in health-related online sites must minimize conflicts of interest and commercial biases and, if patient specific information is transmitted, they must provide high-level security protections, as well as privacy and confidentiality safeguards. (shrink)

Guilt- and shame-prone responding were examined in a sample of 146, 18-month-old toddlers and their older siblings (M = 49.5 months, SD = 10.4) during mishap tasks which were used to differentiate both toddlers and their older siblings into Amenders (low avoidance) and Avoiders (high avoidance). Toddlers and older siblings classified as Amenders expressed more concern and were less distressed by the mishap than Avoiders. Children were divided into four groups: Amender-Amender (older sibling-toddler), Amender-Avoider, Avoider-Avoider, and Avoider-Amender to examine differences (...) in sibling interaction and moral development. Older siblings in the Avoider-Avoider group were significantly more aggressive and less empathic toward toddlers than older siblings in the Avoider-Amender group. Toddlers in the Amender-Amender, Amender-Avoider, and Avoider-Amender groups showed significant gains in moral regulation from 18 to 24 months whereas toddlers in the Avoider-Avoider group did not. In contrast, while older siblings were generally high on moral regulation when toddlers were 18 months, this was not the case for older siblings in the Avoider-Avoider group, who had lower moral regulation scores that significantly increased over time. Findings are discussed with respect to the significance of sibling socialisation for toddlers’ developing moral sensibility. (shrink)

A contribution to the sixth installment of the Common Knowledge symposium “Apology for Quietism,” this article explores the possibilities for quietist narrative. Since quietism suggests resistance or condescension to telos, suspense, will, and the kinds of spirituality, politics, and ways of being associated with them, it seems unlikely that a narrative would be written or read by a practitioner of “ideal indifference” or by anyone averse on principle to initiative. But Gilbert White's text of 1789, The Natural History and Antiquities (...) of Selborne comes as close to being a quietist narrative as is conceivable. Describing the environment of a single English parish, White's text places stillness on exhibit as an indication of commitment to an ethics of self-unregarding attentiveness. But the stillness of Selborne, King argues, is a conspicuous stillness—a practice of being still in face of the natural world. As an Anglican minister, White explicitly demonstrates the arguments of eighteenth-century natural theology. Having stilled his will to interfere, he can observe the activity of God's creations; and White does so in order to understand God better. Thus, White's desisting or withdrawal is in no way based in defeatism, indolence, or aimlessness. Moreover, King argues, White aims to produce stillness as a formal quality of his text and, through it, to produce a like stillness and attentiveness in the reader. Quietist narrative is meant to help the reader still his or her acquisitiveness and develop instead observational capabilities, a capacity simply to admire (or stand apart, in awe), and, above all, patience. To the extent that it fosters in us a principled “do nothing” stance with respect to our natural ecology, King concludes, quietism of Gilbert White's kind may represent the most radical of environmental politics. (shrink)

In this essay I seek to identify and explore a type of intrapersonal division. There is, I argue, a sense in which we may speak of parts of the self, in which those parts interact much as persons do. An account of the genesis and development of parts of the self is given. A taxonomy of the various possible structures of self, based on number and interaction of parts, is used to understand ascriptions of internal harmony or discord to the (...) self. This taxonomy is then used to evaluate the traditional philosophical preference for harmony over internal discord, as well as to examine critically more recent preferences for discord over harmony. This evaluation concentrates on the extent to which images of political community and civil strife figure in philosophical attempts to understand and evaluate interactions among the parts of a person. The limits to which the analogy between interpersonal and intrapersonal relations can be pushed is used to explore the sense in which all of the parts of a person belong to that person. (shrink)

Translation of "Picturing Power: Representation and Las Meninas" (2006).

This paper argues that Descartes conceives of theoretical reason in terms derived from practical reason, particularly in the role he gives to the passions. That the passions serve — under normal circumstances — to preserve the union of mind and body is a well-known feature of Descartes's defense of our native make-up. But they are equally important in our more purely theoretical endeavors. Some passions, most notably wonder, provide a crucial source of motivation in the search after truth, and also (...) serve to reinforce memory. Our cognitive successes and failure scan also be tracked by passions and trains of passions. (shrink)

By reading the analyses of mysticism found in Beauvoir and Irigaray with and against some medieval women's mystical texts, the paper articulates a possible space for the divine within feminist thought.

The presence of fetal cells has been associated with both positive and negative effects on maternal health. These paradoxical effects may be due to the fact that maternal and offspring fitness interests are aligned in certain domains and conflicting in others, which may have led to the evolution of fetal microchimeric phenotypes that can manipulate maternal tissues. We use cooperation and conflict theory to generate testable predictions about domains in which fetal microchimerism may enhance maternal health and those in which (...) it may be detrimental. This framework suggests that fetal cells may function both to contribute to maternal somatic maintenance (e.g. wound healing) and to manipulate maternal physiology to enhance resource transmission to offspring (e.g. enhancing milk production). In this review, we use an evolutionary framework to make testable predictions about the role of fetal microchimerism in lactation, thyroid function, autoimmune disease, cancer and maternal emotional, and psychological health.Also watch the Video Abstract. (shrink)

This book showcases the best in modern medieval and religious scholarship, deploying spirited and progressive approaches to the study of Christian mysticism and the philosophy of religion. The volume explores excessive forms of desire and eroticism at play within Christian mystical texts and the historiographical, theological, and philosophical problems bound up in the interrogation of extraordinary experiences of the divine. Amy Hollywood examines how feminist and queer studies have changed the history of mysticism and how the study of religion in (...) general has altered our understanding of what is true, what is real, and what it means to research a historical subject. Ideal for novices and experienced scholars alike, this volume models cutting-edge methods for the ethical study of divine embodiment and religious experience in the Middle Ages. It makes a forceful case for thinking about religion as both belief and practice, in which traditions marked by change are passed down through generations, laying the groundwork for their own critique. Through a provocative integration of medieval sources and texts by Derrida, Butler, Asad, and Chakrabarty this book redefines what it means to engage critically with history and those embedded within it. (shrink)

Thomas Hobbes claims that the sovereign of a commonwealth provides a “common measure,” determining what counts as right reason for its subjects. As a form of public reason, this is often taken to be a purely political notion. I maintain that Hobbes holds that the public reason of the sovereign also provides a number of epistemic benefits both to the commonwealth and to individuals. Some are a matter of providing conditions that allow for the social growth of knowledge (particularly what (...) Hobbes calls “science”). But I argue that by considering the mechanics of processes of reckoning, we can see that the public reason of the sovereign serves important epistemic functions in the practical reason even of private individuals. (shrink)

Research on language processing has shown that the disruption of conceptual integration gives rise to specific patterns of event-related brain potentials —N400 and P600 effects. Here, we report similar ERP effects when adults performed cross-domain conceptual integration of analogous semantic and mathematical relations. In a problem-solving task, when participants generated labeled answers to semantically aligned and misaligned arithmetic problems, the second object label in misaligned problems yielded an N400 effect for addition problems. In a verification task, when participants judged arithmetically (...) correct but semantically misaligned problem sentences to be “unacceptable,” the second object label in misaligned sentences elicited a P600 effect. Thus, depending on task constraints, misaligned problems can show either of two ERP signatures of conceptual disruption. These results show that well-educated adults can integrate mathematical and semantic relations on the rapid timescale of within-domain ERP effects by a process akin to analogical mapping. (shrink)

The COVID-19 pandemic has brought the live music industry to an abrupt halt; subsequently, musicians are looking for ways to replicate the live concert experience virtually. The present study sought to investigate differences in aesthetic judgments of a live concert vs. a recorded concert, and whether these responses vary based on congruence between musical artist and piece. Participants made continuous ratings of their felt pleasure either during a live concert or while viewing an audiovisual recorded version of the same joint (...) concert given by a university band and a United States Army band. Each band played two pieces: a United States patriotic piece and a non-patriotic piece. Results indicate that, on average, participants reported more pleasure while listening to pieces that were congruent, which did not vary based on live vs. lab listening context: listeners preferred patriotic music when played by the army band and non-patriotic music when played by the university band. Overall, these results indicate that felt pleasure in response to music may vary based on listener expectations of the musical artist, such that listeners prefer musical pieces that “fit” with the particular artist. When considering implications for concerts during the COVID-19 pandemic, our results indicate that listeners may experience similar degrees of pleasure even while viewing a recorded concert, suggesting that virtual concerts are a reasonable way to elicit pleasure from audiences when live performances are not possible. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Ideas 63.3 (2002) 399-424 [Access article in PDF] Representation and the Body of Power in French Academic Painting Amy M. Schmitter [Figures] Reputation of power, is Power... Hobbes, Leviathan, Bk. I, ch. x Introduction It seems natural, even obvious, to distinguish between representations and what they are representations of. A picture of a dog is no more a dog than the word "dog" is (...) a furry, tail-wagging mammal. Nor are properties belonging to the object of a representation necessarily properties of the representation: a picture of a big dog need not be big, a picture of a dog that resembles Fido need not resemble Fido; even a picture of brown Fido need not be brown. And no number of pictures of Fido will sympathetically induce changes in Fido or any other dog. But however clear-cut this distinction may be when what is in question are pictorial references to ordinary, middle-sized material particulars such as dogs, it is much less clear in other cases. It is no violation of common-sense to consider "representations" of such things as gender norms or national identities or selves as non-neutral in the face of what they represent. The representations of gender norms, for example, can extend and enforce them, can change or undermine them, and may well lend a hand in constituting them in the first place.My theme here is a form of pictorial representation, one found in the theory and practice of that strain of French Academic painting under Louis XIV associated with Charles LeBrun. LeBrun held the titles of First Painter to the King and Director of the French Royal Academy of Painting, and the works I will examine were devoted to the royal power. That one effect of royal power is the ability to command resources and to cause the proliferation of representations, especially flattering representations, is no surprise. But I intend to suggest something stronger: not only did these Academic representations present an expenditure [End Page 399] of royal power, they were meant to embody and therefore extend royal power—even to constitute royal power. The view under examination does not simply collapse the common-sense distinction between signifying properties and what is signified; indeed those relations play an important role in one concept of representation modeled on language and written texts. But to this the academicians added another, more robust concept, one that does not distinguish clearly between the representation and its object.Implausible as this view may seem at first blush, I think it can prove genuinely explanatory: explanatory for thinking about pictorial representation, about how it can operate (on both its object and its viewer), and about its relation to power. But to see its explanatory value demands considering the nature and needs of state power. For unlike middle-sized material particulars, state power requires recognition to exist. Although that recognition need not be explicit, conscious, or voluntary, it must be widespread, and pictorial representations can be a powerful device for eliciting such recognition. Yet state power in general— or at least the particular form in question here—may demand that the constitutive role of recognition be disguised. Indeed many of the views and concepts of pictorial representation developed by the Academy reverse the dependence of power on recognition; they function in an ideology of representation. Nonetheless, I think that certain "formal," or structural, features of LeBrun's works can be explained in terms of how they elicit recognition and constitute this particular form of royal power. I make no claim that LeBrun's works must be explained so: for one, the royal power represented by LeBrun's works is long gone, and his representations do not now have any miraculous power to raise the dead. For any representations actually to operate as I suggest requires the support of a whole complex of institutions and activities committed to the care and feeding of state power. It is only because such a complex did exist that LeBrun's representations could have a recognizable object, i... (shrink)

Explores a postmodern criticism of P. S. Churchland's claims regarding materialism. Materialism is classically understood to be the philosophical position which holds that matter is the fundamental reality of the world, and so neurobiological explanations can be said to be materialistic. Neurobiological explanations of behavior are used increasingly in the place of psychological explanations. This trend is indicative of the rise in popularity of materialism. Churchland is one of the intellectual leaders in the modern manifestation of materialism. She is a (...) self-proclaimed materialist and "neurophilosopher." In order for Churchland to maintain her materialist position, she must assume a transparency in scientific method, an assumption which is a legacy of Enlightenment philosophy. However, many postmodern philosophers including M. Heidegger and H. G. Gadamer have questioned this assumed transparency of method. The implications of this postmodern philosophy for the current materialistic trends in psychology are discussed. 2012 APA, all rights reserved). (shrink)

This Report examines the ethical implications of electronic communication, focusing on the use of electronic mail (e-mail), considers its impact on a previously established patient-physician relationship, and the limitations in using e-mail to create a new patient-physician relationship. In its recommendations, this report offers guidance to physicians who use electronic mail to communicate with patients and online users. These guidelines maintain that e-mail should not be used to establish a patient-physician relationship, but rather to supplement personal encounters. When using e-mail, (...) physicians hold the same ethical responsibilities to their patients as they do during other encounters and that information must be presented in a manner that meets professional standards. The report requires that physicians notify patients of e-mail's inherent limitations and that patients be given the opportunity to accept these limitations prior to the communication of privileged information. Finally, physicians should be aware of privacy and confidentiality concerns when using e-mail to communicate with patients. (shrink)

A very welcome addition to the Oxford New Histories of Philosophy, this new edition of Shepherd’s 1827 book comprises the lengthy ‘Essay on the Academical or Sceptical Philosophy’ and fourteen shor...

This chapter contains sections titled: Editor's Prologue Descartes John Locke John Stuart Mill.

To what extent does payment method (managed care vs. out of pocket) influence the likelihood that an independent practitioner will assign a Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 1994) diagnosis to a client? When a practitioner does diagnose, how does payment method influence the specific choice of a diagnostic category? Independent practitioners responded to a vignette describing a fictitious client with symptoms of depression or anxiety. In half of the vignettes, the fictitious client intended to pay (...) via managed care; in the other half, the fictitious client intended to pay out of pocket. Payment method had a very significant impact on diagnosis such that relative to out-of-pocket clients, managed care clients were much more likely to receive diagnoses and more likely to receive adjustment disorder diagnoses in particular. We discuss implications involving informed consent and other ethical issues. (shrink)

Eukaryotic genomes harbor a large number of homologous repeat sequences that are capable of recombining. Their potential to disrupt genome stability highlights the need to understand how homologous recombination processes are coordinated. The Saccharomyces cerevisiae Rad1–Rad10 endonuclease performs an essential role in recombination between repeated sequences, by processing 3′ single‐stranded intermediates formed during single‐strand annealing and gene conversion events. Several recent studies have focused on factors involved in Rad1–Rad10‐dependent removal of 3′ nonhomologous tails during homologous recombination, including Msh2–Msh3, Slx4, and (...) the newly identified Saw1 protein. Together, this new work provides a model for how Rad1–Rad10‐dependent end processing is coordinated: Msh2–Msh3 stabilizes and prepares double‐strand/single‐strand junctions for Rad1–Rad10 cleavage, Saw1 recruits Rad1–Rad10 to 3′ tails, and Slx4 mediates crosstalk between the DNA damage checkpoint machinery and Rad1–Rad10. (shrink)

Whatever may be its other sins, the history of philosophy cannot be faulted for the fleetingness of its memory: "modern" philosophy, after all, is supposed to begin with a figure born 400 years ago, René Descartes. Indeed, even the view that it began then can trace its ancestry back to Descartes. But it would be historically naïve simply to agree with Descartes's self-congratulatory myth of creating a new philosophy ex nihilo. His achievement was a tremendous one, rightfully seen as provoking (...) a sea-change in the history of philosophy, but it was accomplished as much by reflecting on what had gone before as by any other means. One area where Descartes induced the philosophical seas to change can be found in the understanding of causation, and there Descartes clearly took issue with his predecessors, particularly his scholastic predecessors. His quarrel with scholastic natural philosophy over the place of final causes is already well-known, but Descartes took aim just as frequently at the scholastic theory of species, a theory that is a response primarily to questions about "formal" causation in perception and conception. This is in spite of the use Descartes himself sometimes made of 'form': both in such mysterious notions as formal reality and in such supposedly de-mystified ones as the mathematically describable shape of parts of extension. But he did expressly reject the theory of species, and much of the metaphysics that went with it, thereby putting the role and importance of formal causation up for grabs, and changing the nature and range of acceptable explanation in many areas. (shrink)

Many contemporary social epistemologists take themselves to be combatting an individualist approach to knowledge typified by Descartes. Although I agree that Descartes presents an individualist picture of scientific knowledge, he does allow some practical roles for reliance on the testimony and beliefs of others. More importantly, however, his reasons for committing to individualism raise important issues for social epistemology, particularly about how reliance on mere testimony can propagate prejudices and inhibit genuine understanding. The implications of his views are worked out (...) more fully by some of his immediate successors; I examine how François Poulain de la Barre, and (briefly) Mary Astell analyze the social conditions for epistemic agency in a Cartesian vein. (shrink)

Review Essay of Keith Moxey, The Practice of Persuasion: Paradox and Power in Art History.

Is Descartes the most misunderstood philosopher in the history of philosophy? To many of us in the business of Descartes scholarship, it certainly seems so. Time and time again, we find ourselves faced with pronouncements about one or another of Descartes's 'errors' — whether the shortcomings of the theater model of consciousness, or the pernicious after-effects of a foundationalism devoted to the transparency of the mental, or the shocking vilification of the body and emotions. Typically these pronouncements are paired with (...) exhortations to overcome the Cartesian X, where 'X' stands for whatever item crucial to enlightenment is currently most misunderstood. That X is some term rarely used and drastically .. (shrink)